Objective To analyze the effects of Computer Assisted Rehabilitation Environment （CAREN） and traditional Chinese medicine therapy on spastic hemiplegic patients after stroke. Methods A total of 90 patients with post stroke myodystonia treated in Sichuan 81 Rehabilitation Center from March 2015 to March 2016 were selected and grouped by digital random method. In group A（ n=30）， CAREN combined with traditional Chinese medicine therapy was applied. In group B（ n=30）， traditional Chinese medicine acupuncture and moxibustion combined with physical therapy was applied. In group C（ n=30）， the patients were treated with the CAREN combined with traditional physical therapy. The efficacy was evaluated by mobile ability assessment （Functional Independence Measure， FIM）， modified Barthel Index and muscle tension assessment（ modified Ashworth scale）. Results The scores of muscle tension assessment（ modified Ashworth scale）， daily living ability（ modified Barthel Index） and mobile ability assessment（ FIM） of group A were all better than those in group B and C. At the same time， group B was better than group C in the assessment of the above scales， and the differences between groups were statistically significant（ P＜ 0.05）. Conclusions CAREN rehabilitation system combined with traditional Chinese medicine therapy has obvious clinical effect on the recovery of unilateral spasticity of hemiplegic patients after stroke.