Dopamine dysregulation syndrome（ DDS） is a clinical syndrome that produces a series of psychological and behavioral abnormalities due to the addiction to dopaminergic drugs， most commonly found in patients with Parkinson disease who are under dopaminergic replacement therapy. This article reviews the research progress of dopamine dysregulation syndrome in Parkinson disease in terms of the risk factors， pathogenesis， clinical manifestations， diagnosis， evaluation， treatment， and prognosis.