Objective To explore personality traits and their correlation with clinical symptoms in patients with first-episode drug-naive somatic symptom disorder （SSD）. Methods From November 2020 to September 2021， 33 cases of first-episode drug-naive SSD patients attending Renji Hospital Affiliated to Shanghai Jiaotong University School of Medicine were enrolled in study group， while 33 healthy volunteers matched for age， gender， and education level were recruited as healthy controls. Hamilton Depression Scale （HAMD）， Hamilton Anxiety Scale （HAMA）， Symptom Checklist （SCL-90）， and Eysenck Personality Questionnaire-Revised Short Scale for Chinese （EPQ-RSC） were used to assess the subjects' depressive disorder， anxiety， mental health， and personality traits. Pearson correlation and multiple linear regression were used to analyze the relationship between personality trait and depressive， anxiety， and mental health in study group. Results HAMD， HAMA， and SCL-90 total scores of SSD patients were 8.0（6.0，11.0），9.0（6.0，10.0）， and 54.0（32.0，80.5）， respectively， which were statistically significant differences when compared with healthy controls （all P ＜ 0.05）. The difference in introversion and extraversion and neuroticism between SSD patients and healthy controls was statistically significant （P ＜ 0.05）. In SSD patients， introversion and extraversion were negatively correlated with total HAMD score and total SCL-90 score （r=-0.444， -0.362，all P ＜ 0.05）， and neuroticism was positively correlated with total HAMD score and total SCL-90 score （r=0.346， 0.628，all P ＜ 0.05）. In multiple regression analyses of the impact of personality tratis on the clinical symptoms of SSD patients， the final independent variables included in the model were introversion and extraversion when the total HAMD score was used as the dependent variable （P＜ 0.05）， gender and introversion and extraversion when the total HAMA score was used as the dependent variable （P＜ 0.05）， and gender and neuroticism when the total SCL-90 score was used as the dependent variable （P＜ 0.05）. Conclusions SSD patients may have personality traits of introversion and neuroticism， with introversion being associated with their emotional problems and neuroticism being closely related to their overall mental health