OCT及OCTA在鞍区肿物患者视功能评估中的应用进展
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山西省基础研究计划( 20210302123352);山西省卫生健康委科研课题( 2022052);山西省回国留学人员科研资助项目( 2022-205);山西省医学重点科研项目( 2022XM21)


Application progress of OCT and OCTA in visual function assessment of patients with sellarmasses
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    摘要:

    鞍区肿物压迫视通路可导致视功能障碍,其中最常见的病变为垂体腺瘤。肿瘤压迫不同 部位可引发不同类型的视功能障碍,典型表现为双颞侧视野缺损。视力和视野检查在临床评估中至关 重要,但常受到主观因素和设备因素限制的影响。光学相干断层扫描(OCT)作为一种非接触、无创的成 像技术,通过评估视盘周围视网膜神经纤维层(RNFL)厚度和黄斑区神经节细胞复合体(GCC)的厚度变 化,为早期诊断提供了重要依据。光学相干断层扫描血管成像(OCTA)通过检测视网膜不同层次的血管 密度进一步提供了量化指标,也为早期诊断和治疗效果的评估提供了重要的量化依据,显著提高了视 功能评估的敏感度和准确度。近年来,OCT及OCTA 技术在鞍区肿物患者视功能评估中的应用价值逐 渐显现。现主要探讨OCT及OCTA 技术在评估鞍区肿物患者视功能方面的最新进展,以为临床医生提 供更加全面的视功能评估方案,从而改善患者的治疗效果和生活质量。

    Abstract:

    The compression of the optic pathway by the sellar masses can lead to visual dysfunction, with the most common lesion being pituitary adenoma. Tumor compression on different parts can cause different types of visual dysfunction, typically manifested as bilateral temporal visual field defects. Visual acuity and visual field examination are crucial in clinical evaluation, but are often limited by subjective and equipment factors. Optical coherence tomography( OCT), a non-contact, non-invasive imaging technique, provides an important basis for early diagnosis by assessing the thickness of the retinal nerve fiber layer( RNFL) around the optic disc and the thickness changes of the macular ganglion cell complex( GCC). Optical coherence tomography angiography( OCTA) further provides quantitative indexes by detecting the density of blood vessels at different levels of the retina. Also, it provides an important quantitative basis for early diagnosis and assessment of treatment effects, significantly improving the sensitivity and accuracy of visual function assessment. In recent years, the application value of OCT and OCTA techniques in the evaluation of visual function in patients with sellar mass has gradually emerged. This article mainly explores the latest progress of OCT and OCTA techniques in evaluating the visual function of patients with sellar masses, in order to provide clinicians with a more comprehensive visual function assessment plan, thereby improving the treatment effect and quality of life of patients.

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薛晓波,胡昌辰. OCT及OCTA在鞍区肿物患者视功能评估中的应用进展[J].神经疾病与精神卫生,2025,25(10):726-731
DOI :10.3969/j. issn.1009-6574.2025.10.006.

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  • 在线发布日期: 2025-10-20