孤独症谱系障碍儿童的感觉异常与患儿症状、行为及功能的相关性分析
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广东省中医药局科研项目( 20221046)


Correlation between sensory abnormalities and symptoms, behaviors, and function in children withautism spectrum disorder
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    摘要:

    目的 分析孤独症谱系障碍(ASD)儿童感觉异常与患儿症状、行为及功能的相关性。 方法 选取2022 年3 月—2024 年3 月于广东省妇幼保健院接受康复训练的696 例4~6 岁ASD 儿童作为 研究对象,采用儿童感觉统合能力评定量表、孤独症行为评定(ABC)量表、儿童神经心理行为检查量表、 社交反应量表(SRS)、功能独立性评定量表(WeeFIM)评定患儿的感觉统合能力、行为、功能独立性。根 据儿童感觉统合能力评定量表总分分为轻度失调组(总分≥ 90 分,n=104)、中度失调组(总分> 60~< 90分,n=267)、重度失调组(总分≤60分,n=325),比较3组患儿的ABC量表、儿童神经心理行为检查量表、 SRS、WeeFIM 评分差异。采用Pearson 相关分析患儿的儿童感觉统合能力评定量表评分与ABC、儿童神 经心理行为检查量表、SRS、WeeFIM 评分的相关性。结果 3 组患儿的ABC 量表、儿童神经心理行为检 查量表、SRS、WeeFIM 评分比较,差异均有统计学意义(F=905.384、304.753、303.085、5 111.844,均P< 0.05)。儿童感觉统合能力评定量表总分与ABC 量表总分、SRS 总分均呈正相关(r=0.640、0.744,均P < 0.05)。儿童感觉统合能力评定量表总分与儿童神经心理行为检查量表各能区评分及WeeFIM 总分呈负 相关(r=-0.857、-0.567、-0.685、-0.754、-0.522,均P< 0.05)。结论 感觉异常在ASD 患儿中普遍存在, 且患儿感觉异常程度与其症状、行为及功能缺陷严重程度呈正相关。

    Abstract:

    Objective To explore the correlation between sensory abnormalities and symptoms, behaviors, and function in children with autism spectrum disorder( ASD). Methods A total of 696 children aged 4 to 6 years with ASD who underwent rehabilitation training at the Guangdong Provincial Maternal and Child Health Hospital from March 2022 to March 2024 were selected as study subjects. The children's sensory integration ability, behavior, and functional independence were evaluated using the Sensory Integration Ability Rating Scale for Children, Autism Behavior Checklist( ABC), Children Neuropsychological Behavioral Scale, Social Responsiveness Scale( SRS), and Wee Functional Independence Measure( WeeFM). Based on the total scores of the Sensory Integration Ability Rating Scale for Children, children were divided into mild disorder group( ≥90 points, n=104), moderate disorder group( >60 to <90 points, n=267), and severe disorder group (≤ 60 points, n=325). Differences in scores of ABC, Children Neuropsychological Behavioral Scale, SRS, and WeeFIM among the three groups of pediatric patients were compared. Pearson correlation was used to analyze the correlation between scores on the Sensory Integration Ability Rating Scale for Children and scores on the ABC, Children Neuropsychological Behavioral Scale, SRS, and WeeFIM. Results Statistically significant differences were observed in ABC, Children Neuropsychological Behavioral Scale, SRS, and WeeFIM scores among the three groups of pediatric patients( F=905.384, 304.753, 303.085, 5 111.844; all P< 0.05). The total scores of the Sensory Integration Ability Rating Scale for Children showed positive correlations with both the ABC total score and the SRS total score( r=0.640, 0.744; both P < 0.05). The total score of the Sensory Integration Ability Rating Scale for Children showed negative correlations with each functional domain of the Children Neuropsychological Behavioral Scale and the total score of the WeeFIM( r=-0.857,-0.567, -0.685,-0.754,-0.522; all P < 0.05). Conclusions Sensory abnormalities are prevalent among children with ASD, and the severity of sensory abnormalities correlates positively with symptoms, behaviors, and function defects.

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周达龙,黄嘉慧,施嘉英,罗鑫刚.孤独症谱系障碍儿童的感觉异常与患儿症状、行为及功能的相关性分析[J].神经疾病与精神卫生,2025,25(11):810-
DOI :10.3969/j. issn.1009-6574.2025.11.008.

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  • 在线发布日期: 2025-11-21