Geriatric psychiatry， as an essential part of psychiatry， has gradually changed from only caring about the physical and mental health of the elderly to a subject of brain science for the elderly. Due to the complex pathogenesis and poor therapeutic effect， the research of psychiatric disorder in the elderly is faced with great challenges， and more innovative and effective prevention and treatment strategies are urgently needed. This paper briefly reviews the research progress in the pathophysiological mechanism and treatment of common psychiatric disorder in the elderly， hoping to draw more attention to the psychiatric disorder in the elderly.