Parkinson disease（ PD） is one of the most common movement disorders， however， PD with pregnancy is rare. The incidence of PD during pregnancy is low， being difficult to select drugs in the presence of fluctuation symptoms， with complex side effects. With the increase of the average maternal age， the phenomenon of PD combined pregnancy is increasingly common. This paper will discuss the impact of pregnancy on PD， the selection of anti-Parkinson drugs and their impact on the fetus， deep brain stimulation， breastfeeding and prognosis.