Violent and aggressive behaviors in schizophrenia has become one of the problems affecting society and public health. Studies have shown that the violent crime rate of schizophrenia patients is 4-7 times higher than that of the general population. Biological factors such as genetics， neurobiochemistry and metabolism play important roles in the violent and aggressive behaviors of patients with schizophrenia. Therefore， it is of great significance to study the biological mechanism of violence and aggressive behavior in schizophrenia. This review focuses on the biological research progress of violence and aggressive behavior in schizophrenia.