Ischemic stroke is the common type of stroke， with the characteristics of high recurrence rate and high disability， and has become one of the main causes of death and disability. Platelet plays an important role in the pathogenesis of ischemic stroke. In recent years， studies have found that platelet related ratio has important clinical value in predicting the prognosis and outcome of ischemic stroke. In this review， we summarize the recent development of prognostic relevance between derived platelet-related ratios and ischemic stroke， such as the mean platelet volume-to-platelet count （MPV/PC） ratio， platelet-to-lymphocyte ratio （PLR）， mean platelet volume-to-lymphocyte ratio （MPVLR）， platelet-to-neutrophil ratio （PNR）， red blood cell distribution width-to-platelet ratio （RPR）.