Ischemic stroke has a high morbidity， disability and fatality rate， which brings a huge burden to the patient's family and society. Mitochondria are known as the power factories of cells， which are extremely sensitive to changes in blood oxygen and play a key role in maintaining cellular metabolism. In recent years， more and more studies have shown that mitochondrial dynamics and mitophagy are closely related to the occurrence of cerebrovascular diseases. This article mainly summarizes the mechanisms of mitochondrial dynamics and mitophagy and their roles in ischemic stroke， to provide new ideas for the diagnosis and treatment of ischemic stroke.