Alzheimer disease （AD） is the most common type of dementia， and its incidence is increasing year by year. However， the lack of specific therapeutic drugs brings a heavy burden to patients' families and society. Repetitive transcranial magnetic stimulation （rTMS） is a mature non-invasive neuroregulatory technique widely used in the clinical adjuvant treatment of various neuropsychiatric diseases. At present， rTMS achieves certain effects in the treatment of AD， but further research is needed on how to select the optimal stimulation target， frequency and other treatment parameters. This paper starts with optimizing stimulation parameters of rTMS， and reviews the effectiveness and possible mechanisms of rTMS， with the aim of providing guidance for rTMS in the treatment of AD.