Objective To investigate the effects of urine dry chemical indexes on the detection level of Alzheimer-associated neuronal thread protein（ AD7c-NTP） in the elderly population. Methods A total of 455 health examination subjects from the Affiliated Hospital of Guilin Medical University from July 2021 to March 2022 were selected as participants. Urine samples were collected， the concentration of AD7c-NTP were detected by enzyme-linked immunosorbent assay（ ELISA）， the urine dry chemical indicators were detected by dry chemical analyzer. Non-parametric test was used to analyze the effects of urine dry chemical indexes on AD7c-NTP levels， partial correlation test was used to analyze the correlation between urine dry chemical indexes and AD7c-NTP. Results The urine AD7c-NTP level in men was lower than that in women， and the difference was statistically significant（ P＜0.05）. There was significant difference in the level of AD7c-NTP among different age groups（ P＜0.01）. There were no significant differences in the levels of AD7c-NTP in different subgroups of pH， specific gravity， nitrite and glucose in male urine dry chemistry indexes（ all P ＞ 0.05）； There were significant differences in AD7c-NTP levels among different subgroups of people with turbidity， occult blood， granulocyte esterase and urinary protein（ all P＜0.05）. There was no correlation between AD7c-NTP level and urine turbidity， pH value， specific gravity， nitrite， glucose in male urine dry chemical indicators（ all P＞0.05）； The level of AD7c-NTP was correlated with the degree of occult blood in urine， granulocyte esterase and urinary protein（ all P＜0.05）. There were no significant differences in the levels of AD7c-NTP in different subgroups of female urine dry chemical indicators， such as pH value， specific gravity， glucose and occult blood（ all P＞0.05）； The levels of AD7c-NTP in different subgroups of turbidity， nitrite， granulocyte esterase and urinary protein were significantly different（ all P＜0.05）. There was no correlation between urine pH， specific gravity， glucose and AD7c-NTP levels in female（ all P ＞0.05）； Urine turbidity， nitrite， occult blood， granulocyte esterase and urine protein were correlated with AD7c-NTP levels（ all P＜0.05）. Conclusions The urine nitrite， occult blood， granulocytic esterase and protein of dry chemical indexes were correlated with AD7c-NTP， the interpretation of AD7c-NTP detection results in clinical application should refer to urine dry chemical indexes.