In recent years， with the technological development of several medical fields such as molecular genetics， pathology and imaging， neurodegenerative diseases have made significant breakthroughs in both basic research and clinical practice， and precise diagnosis and treatment have become possible. Therefore， it is crucial to train specialized postgraduates with a precision medicine mindset. This paper applies the concept of precision medicine to the training of postgraduates majoring in neurodegenerative diseases on the basis of the traditional training mode， improves and optimizes the teaching content and teaching methods， and builds a multidisciplinary joint teaching platform， which will improve the clinical diagnosis and treatment ability and research and innovation ability of postgraduates majoring in neurodegenerative diseases， and provide a new idea for the cultivation of compound talents in the field of neurodegenerative diseases.